Partner 07: Cooperativa sociale istituto nazionale per lo studio e il controllo dei tumori e delle malattie ambientali Bernardino Ramazzini

Partner description

The RAMAZZINI (RAM) is a non-profit, independent organization located in Bologna, Italy. It is a social cooperative with more than 30,000 active associates. The RAMAZZINI comprises a Cancer Research Center (Cesare Maltoni Cancer Research Center-CMCRC) with one of the largest and longest-existing programs of carcinogenesis bioassays in Europe, and a GLP certificated Laboratory (GLP Life Test). The toxicological assessment in rats for PPP mixtures will be performed in the animal facility of the CMCRC located in the Castle of Bentivoglio, site of the largest and longest-existing programs of experimental carcinogenesis bioassays in Europe. In 40 years, long-term carcinogenicity studies have been conducted at the CMCRC on more than 200 agents present in the industrial and general environment. The RAMAZZINI has consolidated relationships with numerous scientific institutions and universities, both in Italy and
abroad, as with the United States National Toxicology Program, part of the US National Institute of Environmental Health Sciences, the Johns Hopkins University, the Mount Sinai School of Medicine in New York, the Italian National Institute of Health, the University of Bologna (Italy).


Role in the project

RAM is leading WP4 - Eco-toxicological assessment, focus on animal and humans. RAM will also contribute to WP1 & WP 2 (as the responsible of the Italian Case Study Site, CSS5-Po region).

Involved personnel

Fiorella Belpoggi

Dr. Belpoggi is Director of the Research Area of the CMCRC, Ramazzini Institute and of the GLP Life Test. Dr. Belpoggi has been involved for more than 30 years as pathologist and principal investigator in long-term carcinogenicity bioassays, studying dozens of compounds and agents including pesticides (such
as Mancozeb). Other relevant experiences include the participation in the work of the Advisory Group to Recommend Priorities for the IARC Monographs during 2020–2024.

Daniele Mandrioli2

Dr. Mandrioli is Associate Director CMCRC, Ramazzini Institute. Since 2015, Dr. Mandrioli coordinates and supervises the planning and conduct of different experiments and studies on several compounds and agents of public health interests at the CMCRC, Ramazzini Institute Working together with several scientists of the Cochrane Collaboration and other institutions around the world, including the NIEHS, He is currently involved in different projects on evidence based toxicology and systematic reviews. He is co-task leader of WP 4 (Ecotoxicological assessment)